Auto-oxidation promoted sp3 C–H arylation of glycine derivatives-Reference-Cited by-同舟云学术

Auto-oxidation promoted sp3 C–H arylation of glycine derivatives

Published:2018 Issue:27 Volume:16 Page:4985-4989
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wei Yuanyuan¹²³⁴,Wang Jie¹²³⁴,Wang Yajun¹²³⁴,Yao Xiaoqiang¹²³⁴,Yang Caixia¹²³⁴,Huo Congde¹²³⁴^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Northwest Normal University Lanzhou

3. Gansu 730070

4. China

Abstract

An auto-oxidation promoted sp³ C–H arylation reaction between N-aryl glycine derivatives and electron-rich arenes, leading to the formation of N-aryl α-aryl α-amino acid derivatives, is described. This atom-economical and environmentally benign reaction proceeds smoothly under mild reaction conditions and requires only Brønsted acid and oxygen (balloon). A plausible radical involved mechanism is proposed.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01068D

Reference52 articles.

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