Stimuli-responsive biodegradable and gadolinium-based poly[N-(2-hydroxypropyl) methacrylamide] copolymers: their potential as targeting and safe magnetic resonance imaging probes-Reference-Cited by-同舟云学术

Stimuli-responsive biodegradable and gadolinium-based poly[N-(2-hydroxypropyl) methacrylamide] copolymers: their potential as targeting and safe magnetic resonance imaging probes

Published:2017 Issue:15 Volume:5 Page:2763-2774
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Li Xue¹²³⁴⁵,Sun Ling⁶⁷³⁴⁵,Wei Xiaoli⁶⁷³⁴⁵,Luo Qiang⁶⁷³⁴⁵,Cai Hao⁶⁷³⁴⁵,Xiao Xueyang⁶⁷³⁴⁵,Zhu Hongyan¹²³⁴⁵,Luo Kui⁶⁷³⁴⁵^ORCID

Affiliation:

1. Laboratory of Stem Cell Biology

2. State Key Laboratory of Biotherapy

3. West China Hospital

4. Sichuan University

5. Chengdu

6. Huaxi MR Research Center (HMRRC)

7. Department of Radiology

Abstract

Functionalized and biodegradable block pHPMA copolymer–gadolinium conjugates demonstrated good biocompatibility, high T₁ relaxivity, and enhanced tumor signal intensity for MRI.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C6TB03253B

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1. In Vivo MRI Detection of Gliomas by Chlorotoxin-Conjugated Superparamagnetic Nanoprobes

2. Analysis of volume MRI and MR spectroscopic imaging data for the evaluation of patients with brain tumors

3. Biodegradable Polydisulfide Dendrimer Nanoclusters as MRI Contrast Agents