Two novel oxetane containing lignans and a new megastigmane from Paronychia arabica and in silico analysis of them as prospective SARS-CoV-2 inhibitors-Reference-Cited by-同舟云学术

Two novel oxetane containing lignans and a new megastigmane from Paronychia arabica and in silico analysis of them as prospective SARS-CoV-2 inhibitors

Published:2021 Issue:33 Volume:11 Page:20151-20163
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Elshamy Abdelsamed I.¹²³⁴⁵,Mohamed Tarik A.⁶⁷⁸⁹,Ibrahim Mahmoud A. A.¹⁰¹¹¹²¹³¹⁴^ORCID,Atia Mohamed A. M.¹⁵¹⁶¹⁷¹⁸⁸^ORCID,Yoneyama Tatsuro¹²³⁴,Umeyama Akemi¹²³⁴,Hegazy Mohamed-Elamir F.⁶⁷⁸⁹¹⁹^ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences

2. Tokushima Bunri University

3. Tokushima

4. Japan

5. Chemistry of Natural Compounds Department

6. Chemistry of Medicinal Plants Department

7. National Research Centre

8. Giza

9. Egypt

10. Computational Chemistry Laboratory

11. Chemistry Department

12. Faculty of Science

13. Minia University

14. Minia

15. Molecular Genetics and Genome Mapping Laboratory

16. Genome Mapping Department

17. Agricultural Genetic Engineering Research Institute (AGERI)

18. Agricultural Research Center (ARC)

19. Department of Pharmaceutical Biology

Abstract

The hydromethanolic extract of Paronychia arabica aerial parts afforded two oxetane containing lignans, paronychiarabicine A (1) and B (2), and one new megastigmane, paronychiarabicastigmane A (3), alongside a known secondary metabolites (4–14).

Funder

National Research Centre

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA02486H

Reference63 articles.

1. A Review of the Effects of Natural Compounds, Medicinal Plants, and Mushrooms on the Gut Microbiota in Colitis and Cancer

2. Potential roles of medicinal plants for the treatment of viral diseases focusing on COVID ‐19: A review