Synthesis and characterization of Pt(ii)-based potent anticancer agents with minimum normal cell toxicity: their bio-activity and DNA-binding properties-Reference-Cited by-同舟云学术

Synthesis and characterization of Pt(ii)-based potent anticancer agents with minimum normal cell toxicity: their bio-activity and DNA-binding properties

Published:2019 Issue:47 Volume:43 Page:18767-18779
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Mahata Sujay¹²³⁴,Mukherjee Subhajit¹²³⁴^ORCID,Tarai Swarup Kumar¹²³⁴,Pan Angana¹²³⁴,Mitra Ishani¹²³⁴,Pal Soumojit⁵⁶⁷⁴,Maitra Sudipta⁵⁶⁷⁴,Moi Sankar Ch.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. National Institute of Technology Durgapur

3. Durgapur-713209

4. India

5. Department of Zoology

6. Visva-Bharati University

7. Santinikatan

Abstract

The Cis-Pt(ii)-dichloro complex and its different intercellular derivates show good DNA-binding, comparable anticancer properties and less normal cell toxicity than cisplatin, and initiates cell death through apoptosis.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ03108A

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