Less toxic zinc(ii), diorganotin(iv), gallium(iii) and cadmium(ii) complexes derived from 2-benzoylpyridine N,N-dimethylthiosemicarbazone: synthesis, crystal structures, cytotoxicity and investigations of mechanisms of action
Author:
Affiliation:
1. Henan Key Laboratory of Polyoxometalates
2. Institute of Molecular and Crystal Engineering
3. College of Chemistry and Chemical Engineering
4. Henan University
5. Kaifeng 475004
Abstract
Growth inhibition results showed that 1 exhibited toxicity on QSG7701 cells which was 12-fold lower than that of HepG2 cells.
Funder
National Natural Science Foundation of China
Publisher
Oxford University Press (OUP)
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://pubs.rsc.org/en/content/articlepdf/2018/TX/C8TX00127H
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2. Role of Substitution at Terminal Nitrogen of 2-Oxo-1,2-dihydroquinoline-3-Carbaldehyde Thiosemicarbazones on the Coordination Behavior and Structure and Biological Properties of Their Palladium(II) Complexes
3. Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu(i/ii) complexes of thiosemicarbazone: special emphasis on their interactions with DNA
4. A novel water soluble ligand bridged cobalt(ii) coordination polymer of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA binding, protein interaction, radical scavenging and anticancer activity
5. Cytotoxicity and apoptotic activity of novel organobismuth(V) and organoantimony(V) complexes in different cancer cell lines
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