Efficient and stereoselective synthesis of sugar fused pyrano[3,2-c]pyranones as anticancer agents

Author:

Kumar Sandeep12ORCID,Sahu Ram Krishna3,Kumari Priti1,Maity Jyotirmoy4,Kumar Binayak3,Chhatwal Rajni Johar5,Singh Brajendra K.1ORCID,Prasad Ashok K.1ORCID

Affiliation:

1. Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi-110007, India

2. Department of Chemistry, Ramjas College, University of Delhi, Delhi-110007, India

3. National Institute of Cancer Prevention & Research, Noida, Uttar Pradesh, India

4. Department of Chemistry, St. Stephen College, University of Delhi, Delhi-110007, India

5. Department of Chemistry, Maitreyi College, University of Delhi, Delhi, India

Abstract

A highly stereoselective, efficient and facile route was achieved for the synthesis of novel and biochemically potent sugar fused pyrano[3,2-c]pyranone derivatives starting from inexpensive, naturally occurring d-galactose and d-glucose.

Funder

University of Delhi

Council of Scientific and Industrial Research, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference48 articles.

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3. Global cancer statistics

4. S. K.Kim , Handbook of Anticancer Drugs from Marine Origin , Springer International Publishing , Switzerland , 2015

5. Current developments of coumarin-based anti-cancer agents in medicinal chemistry

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