Biochemical and microbiological evaluation of N-aryl urea derivatives against mycobacteria and mycobacterial hydrolases-Reference-Cited by-同舟云学术

Biochemical and microbiological evaluation of N-aryl urea derivatives against mycobacteria and mycobacterial hydrolases

Published:2019 Issue:7 Volume:10 Page:1197-1204
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Vartak Abhishek¹²³⁴,Goins Christopher⁵⁶⁷⁸⁴,de Moura Vinicius Calado Nogueira⁹¹⁰¹¹¹²¹³,Schreidah Celine M.¹²³⁴,Landgraf Alexander D.¹²³⁴,Lin Boren¹⁴²³⁴^ORCID,Du Jianyang¹⁴²³⁴^ORCID,Jackson Mary⁹¹⁰¹¹¹²¹³,Ronning Donald R.¹²³⁴^ORCID,Sucheck Steven J.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of Toledo

3. Toledo

4. USA

5. Center for Therapeutic Discovery

6. Lerner Research Institute

7. Cleveland Clinic Foundation

8. Cleveland

9. Mycobacteria Research Laboratories

10. Department of Microbiology

11. Immunology and Pathology

12. Colorado State University

13. Fort Collins

14. Department of Biological Sciences

Abstract

N-Aryl urea derivatives were synthesized and some showed activity against mycobacterial hydrolases while others showed antimicrobial activity against mycobacterial species.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00122K

Reference38 articles.

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3. Mechanisms of mycobacterial persistence in tuberculosis