One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine-Reference-Cited by-同舟云学术

One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine

Published:2015 Issue:2 Volume:17 Page:852-855
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Lichman B. R.¹²³⁴^ORCID,Lamming E. D.⁵²³⁴,Pesnot T.⁵²³⁴,Smith J. M.¹²³⁴,Hailes H. C.⁵²³⁴,Ward J. M.¹²³⁴

Affiliation:

1. Department of Biochemical Engineering

2. University College London

3. London

4. UK

5. Department of Chemistry

Abstract

One-pot, one-substrate, triangular chemoenzymatic cascades featuring transaminase (TAm) and norcoclaurine synthase (NCS) enables the formation of (S)-benzylisoquinoline and (S)-tetrahydroprotoberberine alkaloids.

Funder

Wellcome Trust

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/GC/C4GC02325K

Reference39 articles.

1. Green chemistry: challenges and opportunities

2. Atom efficiency and catalysis in organic synthesis

3. New Generation of Biocatalysts for Organic Synthesis

4. Multi-Enzymatic Cascade Reactions: Overview and Perspectives

5. Recent Developments of Cascade Reactions Involving ω-Transaminases

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