Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues-Reference-Cited by-同舟云学术

Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues

Author:

Misawa Takashi¹²³⁴^ORCID,Goto Chihiro¹²³⁴⁵,Shibata Norihito⁶²³⁴,Hirano Motoharu¹²³⁴,Kikuchi Yutaka⁷²³⁴,Naito Mikihiko⁶²³⁴,Demizu Yosuke¹²³⁴⁵^ORCID

Affiliation:

1. Division of Organic Chemistry

2. National Institute of Health Sciences

3. Kawasaki

4. Japan

5. Graduate School of Medical Life Science

6. Division of Molecular Target and Gene Therapy Products

7. Division of Microbiology

Abstract

Amphipathic helical peptideStripeshowed high antimicrobial activity, low hemolytic activity, and low human cell cytotoxicity.

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Terumo Foundation for Life Sciences and Arts

Takeda Science Foundation

Shorai Foundation for Science and Technology

Tokyo Biochemical Research Foundation

Naito Foundation

NOVARTIS Foundation (Japan) for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference27 articles.

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