Post-synthetic conversion of 5-pivaloyloxymethyluridine present in a support-bound RNA oligomer into biologically relevant derivatives of 5-methyluridine-Reference-Cited by-同舟云学术

Post-synthetic conversion of 5-pivaloyloxymethyluridine present in a support-bound RNA oligomer into biologically relevant derivatives of 5-methyluridine

Published:2017 Issue:9 Volume:15 Page:2097-2103
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bartosik Karolina¹²³⁴^ORCID,Sochacka Elzbieta¹²³⁴,Leszczynska Grazyna¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. Lodz University of Technology

3. 90-924 Lodz

4. Poland

Abstract

A reliable post-synthetic method to access the modified RNA oligomers containing biologically important 5-methyluridines: mnm⁵U, cmnm⁵U, τm⁵U, nm⁵U, inm⁵U and cnm⁵U.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C6OB02674E

Reference39 articles.

1. Distribution and frequencies of post-transcriptional modifications in tRNAs

2. Modified Uridines with C5-methylene Substituents at the First Position of the tRNA Anticodon Stabilize U·G Wobble Pairing during Decoding

3. The role of modifications in codon discrimination by tRNALysUUU

4. Possible conformations of 5-aminomethyluridine derivatives recognizing a G at the third position of the codon

5. Roles of 5-substituents of tRNA wobble uridines in the recognition of purine-ending codons

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chemistry of installing epitranscriptomic 5-modified cytidines in RNA oligomers;Organic & Biomolecular Chemistry;2024

2. Aqueous Activation of RNA 2′-OH for Conjugation with Amines and Thiols;Bioconjugate Chemistry;2023-12-27

3. Metal‐free sp²‐C7−H Borylation of Tryptophan Containing Peptides and Late‐stage Modification;Chemistry – An Asian Journal;2023-10-30

4. Post-synthetic modification of oligonucleotides containing 5-mono- and 5-di-fluoromethyluridines;Tetrahedron;2021-01

5. Synthesis of 5‐Cyanomethyluridine (cnm 5 U) and 5‐Cyanouridine (cn 5 U) Phosphoramidites and Their Incorporation into RNA Oligonucleotides;Current Protocols in Nucleic Acid Chemistry;2020-08-26