Development of colloidal rare-earth arsenites as arsenic trioxide nanoparticle prodrugs (ATONP) for chemotherapy on a patient-derived xenograft model of colorectal cancer-Reference-Cited by-同舟云学术

Development of colloidal rare-earth arsenites as arsenic trioxide nanoparticle prodrugs (ATONP) for chemotherapy on a patient-derived xenograft model of colorectal cancer

Published:2019 Issue:44 Volume:43 Page:17408-17415
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Fu Xin¹²³⁴⁵,Zhang Hua-qing⁶⁷⁴⁵,Zhao Jun¹²³⁴⁵,Yu Lu-lu⁸⁴⁵,Liang Qing-rong⁸⁴⁵,Zhang Yu⁹⁴⁵,Yi Xiu-Guang⁹⁴⁵,Li Yong-xiu⁹⁴⁵,Hu Ji-long¹⁰⁴⁵,He Yuan-qiao¹¹⁴⁵,Tang Qun¹²³⁴⁵^ORCID

Affiliation:

1. Jiangxi Provincial Key Laboratory of Preventive Medicine

2. School of Public Health

3. Nanchang University

4. Nanchang

5. P. R. China

6. Department of Hematology

7. the First Affiliated Hospital of Nanchang University

8. Institute for Advanced Study, Nanchang University

9. College of Chemistry, Nanchang University

10. Jiangxi Cancer Hospital

11. Department of Laboratory Animal Science, Nanchang University

Abstract

Rare earth arsenite colloids, acting as arsenic trioxide nanoparticle prodrugs, effectively arrested cancer growth in a patient-derived colorectal xenograft model.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ02990G

Reference20 articles.

1. Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

2. A Novel Nanoparticulate Formulation of Arsenic Trioxide with Enhanced Therapeutic Efficacy in a Murine Model of Breast Cancer

3. Lipid Encapsulation of Arsenic Trioxide Attenuates Cytotoxicity and Allows for Controlled Anticancer Drug Release

4. Inorganic phosphate-triggered release of anti-cancer arsenic trioxide from a self-delivery system: an in vitro and in vivo study

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