Accumulation of small protein molecules in a macroscopic complex coacervate

Author:

Lindhoud Saskia12345,Claessens Mireille M. A. E.12345

Affiliation:

1. Nanobiophysics, MESA+Institute for Nanotechnology

2. Faculty of Science and Technology

3. University of Twente

4. 7500 AE Enschede, The Netherlands

5. MIRA Institute for Biomedical Technology and Technical Medicine

Abstract

By mixing the aqueous solutions of poly acrylic acid, poly-(N,N dimethylaminoethyl methacrylate) and lysozyme, complex coacervates with a protein concentration as high as 200 g L−1 are obtained.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Reference29 articles.

1. H. Bungenberg de Jong , Complex colloid systems , 1949 , vol. 2

2. Reversibility and Relaxation Behavior of Polyelectrolyte Complex Micelle Formation

3. S. Lindhoud and M. A.Cohen Stuart , Relaxation Phenomena During Polyelectrolyte Complex Formation , Springer Berlin Heidelberg , 2014 , vol. 255, pp. 139–172

4. Protein–polyelectrolyte interactions

5. Charge Stoichiometry Inside Polyelectrolyte−Protein Complexes:  A Direct SANS Measurement for the PSSNa−Lysozyme System

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