PEGylation enhances the tumor selectivity of melanoma-targeted conjugates-Reference-Cited by-同舟云学术

PEGylation enhances the tumor selectivity of melanoma-targeted conjugates

Published:2015 Issue:2 Volume:13 Page:388-397
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

André Mathieu¹²³⁴⁵,Besse Sophie¹²³⁴⁵,Chezal Jean-Michel¹²³⁴⁵,Mounetou Emmanuelle¹²³⁴⁵

Affiliation:

1. INSERM - Université d'Auvergne UMR 990

2. IMTV

3. BP 184

4. F-63005 Clermont-Ferrand Cedex

5. France

Abstract

Three preselected conjugates of 5-iodo-2′-deoxyuridine (IUdR) to the ICF01012 melanoma-carrier, PEGylated and non-PEGylated, were radiolabelled with iodine-125, and their in vivo distribution profile was evaluated for potential intratumoural selective delivery.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB01751J

Reference34 articles.

1. Systematic Review of Medical Treatment in Melanoma: Current Status and Future Prospects

2. Targeted anticancer therapy: Overexpressed receptors and nanotechnology

3. Future Cancer Therapy with Molecularly Targeted Therapeutics: Challenges and Strategies

4. Recent Trends in Targeted Anticancer Prodrug and Conjugate Design

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