A multiple-step screening protocol to identify norepinephrine and dopamine reuptake inhibitors for depression-Reference-Cited by-同舟云学术

A multiple-step screening protocol to identify norepinephrine and dopamine reuptake inhibitors for depression

Published:2023 Issue:12 Volume:25 Page:8341-8354
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Wang Panpan¹^ORCID,Yan Fengmei¹,Dong Jianghong¹^ORCID,Wang Shengqiang¹,Shi Yu¹,Zhu Mengdan¹,Zuo Yuting¹,Ma Hui¹,Xue Ruirui¹,Zhai Dingjie¹,Song Xiaoyu¹

Affiliation:

1. College of Chemistry and Pharmaceutical Engineering, Huanghuai University, Zhumadian 463000, China

Abstract

A comprehensive strategy was used that identified six novel NDRIs from compound libraries that were selective against hNET and hDAT. Five compounds showed high activities, and four of them performed balancing activities acting on hNET and hDAT.

Funder

National Natural Science Foundation of China

Key Scientific Research Project of Colleges and Universities in Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CP/D2CP05676C

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