Efficient one-step amide formation using amino porphyrins-Reference-Cited by-同舟云学术

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Efficient one-step amide formation using amino porphyrins

Published:2024 Issue:31 Volume:22 Page:6308-6320
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Vollett Kyle D. W.¹²^ORCID,Cheng Hai-Ling Margaret¹²³^ORCID

Affiliation:

1. Institute of Biomedical Engineering, University of Toronto, Canada

2. Translational Biology & Engineering Program, Ted Rogers Centre for Heart Research, Toronto, Canada

3. The Edward S. Rogers Sr. Department of Electrical & Computer Engineering, University of Toronto, Canada

Abstract

A fast, high-yield one-step reaction is proposed for conjugating an MRI contrast agent to carboxylic acids and is demonstrated for synthesizing a blood-pool contrast agent that reversibly binds to albumin for in vivo vascular MRI.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

Canada Foundation for Innovation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00704B

Reference54 articles.

1. Amide Bond Formation Strategies: Latest Advances on a Dateless Transformation

2. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

3. MRI method for labeling and imaging decellularized extracellular matrix scaffolds for tissue engineering

4. Porphyrin photosensitizers in photodynamic therapy and its applications

5. Molybdenum Diselenide–Manganese Porphyrin Bifunctional Electrocatalyst for the Hydrogen Evolution Reaction and Selective Hydrogen Peroxide Production

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