Antimicrobial and toxicological evaluations of binuclear mercury(ii)bis(alkynyl) complexes containing oligothiophenes and bithiazoles

Author:

Lam P. L.1234,Lu G. L.56789,Choi K. H.56789,Lin Z.6104,Kok S. H. L.11124,Lee K. K. H.11124,Lam K. H.1234,Li H.1314159,Gambari R.1617181920,Bian Z. X.212284,Wong W. Y.56789,Chui C. H.123421

Affiliation:

1. State Key Laboratory of Chirosciences

2. Department of Applied Biology and Chemical Technology

3. The Hong Kong Polytechnic University

4. P. R. China

5. Institute of Molecular Functional Materials

6. Department of Chemistry

7. Partner State Key Laboratory of Environmental and Biological Analysis

8. Hong Kong Baptist University

9. China

10. The Hong Kong University of Science and Technology

11. School of Biomedical Sciences

12. The Chinese University of Hong Kong

13. College of Life and Environmental Sciences

14. Minzu University of China

15. Beijing 100081

16. Centre of Biotechnology

17. Department of Life Sciences and Biotechnology

18. University of Ferrara

19. Ferrara

20. Italy

21. Clinical Division

22. School of Chinese Medicine

Abstract

We investigated the antimicrobial activity of bis-(alkynyl)mercury(ii) complexes with oligothiophene and bithiazole linking units against MRSA and C. albicans, and their cytotoxicity was tested on NIH 3T3 cells.

Funder

Hong Kong Baptist University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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