Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin–agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles

Author:

Eivazzadeh-Keihan Reza12345,Moghim Aliabadi Hooman Aghamirza67859ORCID,Radinekiyan Fateme12345,Sobhani Mohammad12345,Farzane khalili 12345,Maleki Ali12345ORCID,Madanchi Hamid101112135,Mahdavi Mohammad14151685ORCID,Shalan Ahmed Esmail1718192021ORCID

Affiliation:

1. Catalysts and Organic Synthesis Research Laboratory

2. Department of Chemistry

3. Iran University of Science and Technology

4. Tehran 16846-13114

5. Iran

6. Faculty of Chemistry

7. K. N. Toosi University of Technology

8. Tehran

9. Protein Chemistry Laboratory

10. Department of Biotechnology

11. School of Medicine

12. Semnan University of Medical Sciences

13. Semnan

14. Endocrinology and Metabolism Research Center

15. Endocrinology and Metabolism Clinical Sciences Institute

16. Tehran University of Medical Sciences

17. BCMaterials

18. Basque Center for Materials, Applications and Nanostructures

19. Martina Casiano

20. UPV/EHU Science Park

21. Leioa 48940

Abstract

Given the important aspects of wound healing approaches, in this work, an innovative biocompatible nanobiocomposite scaffold was designed and prepared based on cross-linked lignin–agarose hydrogel, extracted silk fibroin solution, and zinc chromite (ZnCr2O4) nanoparticles.

Funder

Consejo Superior de Investigaciones Científicas

Iran University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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