Molecular hybridization as a powerful tool towards multitarget quinoidal systems: synthesis, trypanocidal and antitumor activities of naphthoquinone-based 5-iodo-1,4-disubstituted-, 1,4- and 1,5-disubstituted-1,2,3-triazoles-Reference-Cited by-同舟云学术

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Molecular hybridization as a powerful tool towards multitarget quinoidal systems: synthesis, trypanocidal and antitumor activities of naphthoquinone-based 5-iodo-1,4-disubstituted-, 1,4- and 1,5-disubstituted-1,2,3-triazoles

Published:2016 Issue:8 Volume:7 Page:1555-1563
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Bahia Samara Ben B. B.¹²³⁴⁵,Reis Wallace J.¹²³⁴⁵,Jardim Guilherme A. M.¹²³⁴⁵,Souto Francielly T.¹²³⁴⁵,de Simone Carlos A.⁶⁷⁸⁹⁵,Gatto Claudia C.¹⁰¹¹¹²⁵,Menna-Barreto Rubem F. S.¹³¹⁴¹⁵⁵,de Castro Solange L.¹³¹⁴¹⁵⁵,Cavalcanti Bruno C.¹⁶¹⁷¹⁸⁵,Pessoa Claudia¹⁶¹⁷¹⁸⁵,Araujo Maria H.¹²³⁴⁵,da Silva Júnior Eufrânio N.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Institute of Exact Sciences

3. Federal University of Minas Gerais

4. Belo Horizonte

5. Brazil

6. Department of Physics and Informatics

7. Institute of Physics

8. University of São Paulo

9. São Carlos

10. Institute of Chemistry

11. University of Brasilia

12. Brasilia

13. Oswaldo Cruz Institute

14. FIOCRUZ

15. Rio de Janeiro

16. Department of Physiology and Pharmacology

17. Federal University of Ceará

18. Fortaleza

Abstract

Some of the hybrid compounds exhibited promising trypanocidal and anticancer activities.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00216A

Reference60 articles.

1. Nova tripanozomiaze humana: estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. gen., n. sp., ajente etiolojico de nova entidade morbida do homem

2. The main sceneries of Chagas disease transmission. The vectors, blood and oral transmissions - A comprehensive review

3. Chagas disease: A Latin American health problem becoming a world health problem

4. Oral transmission of Chagas disease: Typing of Trypanosoma cruzi from five outbreaks occurred in Venezuela shows multiclonal and common infections in patients, vectors and reservoirs

5. Oral Transmission of Chagas Disease

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