Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis-Reference-Cited by-同舟云学术

Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis

Published:2021 Issue:43 Volume:11 Page:26594-26606
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yu Yang¹²³⁴⁵,Wu Shifei¹²³⁴⁵,Zhang Jianqing¹²³⁴⁵,Li Jiayuan¹²³⁴⁵,Yao Changliang¹²³⁴⁵,Wu Wenyong¹²³⁴⁵,Wang Yingying¹²³⁴⁵,Ji Hongjian¹²³⁴⁵,Wei Wenlong¹²³⁴⁵,Gao Min¹²³⁴⁵,Li Yun¹²³⁴⁵,Yao Shuai¹²³⁴⁵,Huang Yong¹²³⁴⁵,Bi Qirui¹²³⁴⁵,Qu Hua¹²³⁴⁵,Guo De-an¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Research Center for Modernization of Traditional Chinese Medicine

2. National Engineering Laboratory for TCM Standardization Technology

3. Shanghai Institute of Materia Medica

4. Chinese Academy of Sciences

5. Shanghai 201203

Abstract

In vitro systematic evaluation and network pharmacology analysis to explore the anti-tumor activities of thirty-seven diterpenoid alkaloids (DAs) from Aconitum carmichaelii Debx., including the first reported C₂₀-DA glucoside and three new C₁₉-DAs.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA04223H

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