Chiral determination and assay of optical isomers in clandestine drug laboratory samples using LC-MSMS

Author:

Popovic A.1234ORCID,McBriar T.564,He P.564,Beavis A.12347ORCID

Affiliation:

1. Centre for Forensic Science

2. Faculty of Science

3. University of Technology Sydney

4. Australia

5. NSW Illicit Drug Analysis Unit

6. NSW Forensic & Analytical Science Services

7. Faculty of Transdisciplinary Innovation

Abstract

Development of a method for enantioseparation of amphetamine, methamphetamine and methorphan using LC-MSMS with the aid of a chiral stationary phase.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference47 articles.

1. Ilicit Drug Data Report 2013–14, Australian Crime Commision, 2014, https://www.crimecommission.gov.au/illicit-drug-data-report-2013-14

2. Amphetamine-type stimulants, World Health Organization, 2015, http://www.who.int/substance_abuse/facts/ATS/en/

3. Methamphetamine drug profile European Monitoring Centre for Drugs and Drug Addiction, 2015, http://www.emcdda.europa.eu/publications/drug-profiles/methamphetamine

4. The effect of N-alkyl chain length and stereochemistry on the absorption, metabolism and urinary excretion of N-alkylamphetamines in man

5. D. Jirovsky , J.Sevcika, Z.Andarovab, B.Smyslc, P.Bartaka, P.Bednarb, A.Gavendab and P.Adamovsky, The pilot study of methamphetamine enantiomer metabolism in man by capillary electrophoresis. Chemia, 2001, vol. 40, pp. 25–34

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