Identification of a common recognition center for a photoactive non-steroidal antiinflammatory drug in serum albumins of different species-Reference-Cited by-同舟云学术

Identification of a common recognition center for a photoactive non-steroidal antiinflammatory drug in serum albumins of different species

Published:2019 Issue:1 Volume:6 Page:99-109
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Molins-Molina Oscar¹²³⁴^ORCID,Lence Emilio⁵⁶⁷⁸⁴^ORCID,Limones-Herrero Daniel¹²³⁴^ORCID,González-Bello Concepción⁵⁶⁷⁸⁴^ORCID,Miranda Miguel A.¹²³⁴^ORCID,Jiménez M. Consuelo¹²³⁴^ORCID

Affiliation:

1. Departamento de Química/Instituto de Tecnología Química UPV-CSIC

2. Universitat Politècnica de València

3. 46071 Valencia

4. Spain

5. Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS)

6. Departamento de Química Orgánica

7. Universidade de Santiago de Compostela

8. 15782 Santiago de Compostela

Abstract

Photoreactivity, proteomic and molecular dynamic simulation studies demonstrate the existence of a common recognition center for carprofen in serum albumins of different species, in the interface between subdomains IB and IIIA.

Funder

Secretaría de Estado de Investigación, Desarrollo e Innovación

Generalitat Valenciana

Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia

European Regional Development Fund

Instituto de Salud Carlos III

Xunta de Galicia

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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