Procyanidin A2, an anti-diabetic condensed tannin extracted from Wendlandia glabrata, reduces elevated G-6-Pase and mRNA levels in diabetic mice and increases glucose uptake in CC1 hepatocytes and C1C12 myoblast cells-Reference-Cited by-同舟云学术

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Procyanidin A2, an anti-diabetic condensed tannin extracted from Wendlandia glabrata, reduces elevated G-6-Pase and mRNA levels in diabetic mice and increases glucose uptake in CC1 hepatocytes and C1C12 myoblast cells

Published:2019 Issue:30 Volume:9 Page:17211-17219
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sheikh Yunush¹²³,Chanu Maibam Beebina¹²³,Mondal Gopinath¹²³,Manna Prasenjit⁴⁵³,Chattoraj Asamanja¹²³,Chandra Deka Dibakar⁶⁷⁸³,Chandra Talukdar Narayan⁹¹⁰¹¹¹²³,Chandra Borah Jagat⁹¹⁰¹¹¹²³^ORCID

Affiliation:

1. Institute of Buioresources and Sustainable Development

2. Imphal-795001

3. India

4. CSIR-North East Institute of Science and Technology

5. Jorhat-785006

6. Department of Chemistry

7. Gauhati University

8. Guwahati-781014

9. Laboratory of Natural Medicinal Chemistry

10. Life Sciences Division

11. Institute of Advanced Study in Science & Technology

12. Guwahati-781035

Abstract

Wendlandia glabrata and procyanidin A2 isolated thereof are exhibited significant anti-diabetic effect.

Funder

Department of Biotechnology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA02397F

Reference34 articles.

1. IDF Diabetes Atlas 2017

2. The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives

3. Potential of Polygonum cuspidatum Root as an Antidiabetic Food: Dual High-Resolution α-Glucosidase and PTP1B Inhibition Profiling Combined with HPLC-HRMS and NMR for Identification of Antidiabetic Constituents

4. Re-exploring promising α-glucosidase inhibitors for potential development into oral anti-diabetic drugs: Finding needle in the haystack

5. Inhibition of hepatic glucose 6-phosphatase system by the green tea flavanol epigallocatechin gallate

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