Simultaneous determination of ginkgolides A, B and K in human plasma by UPLC-MS/MS and its application to the pharmacokinetic study of Ginkgo Diterpene Lactone Meglumine Injection in humans-Reference-Cited by-同舟云学术

Simultaneous determination of ginkgolides A, B and K in human plasma by UPLC-MS/MS and its application to the pharmacokinetic study of Ginkgo Diterpene Lactone Meglumine Injection in humans

Published:2016 Issue:11 Volume:8 Page:2341-2348
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Li Yan-Jing¹²³⁴,Zhang Chen-Feng¹²³⁴,Huang Wen-Zhe¹²³⁴,Geng Ting¹²³⁴,Wang Zhen-Zhong¹²³⁴,Zhao Bin-Jiang¹²³⁴,Zhou Yi-Fei¹²³⁴,Xiao Wei¹²³⁴

Affiliation:

1. State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process

2. Jiangsu Kanion Pharmaceutical Co. Ltd

3. Lianyungang 222001

4. China

Abstract

The UPLC-MS/MS method was developed for quantifying ginkgolide A, ginkgolide B and ginkgolide K as hydrolyzed forms in Ginkgo Diterpene Lactone Meglumine Injection for pharmacokinetic studies.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/AY/C5AY02892B

Reference22 articles.

1. P. Del Tredici , in Ginkgo Biloba, ed. T. A. van Beek, Harwood, Amsterdam, 2000, p. 7

2. V. Melzheimer and J. J.Lichius, in Ginkgo Biloba, ed. T. A. van Beek, Harwood, Amsterdam, 2000, p. 25

3. The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF)

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An Overview of Crucial Dietary Substances and Their Modes of Action for Prevention of Neurodegenerative Diseases;Cells;2020-02-28

2. Simultaneous quantification of twelve compounds in ethyl acetate extracts of Euphorbia kansui before and after fry-baked with vinegar by UPLC–MS/MS and its toxic effect on zebrafish;Journal of Pharmaceutical and Biomedical Analysis;2018-06

3. Applying risk management to analytical methods for the desorbing process of ginkgo diterpene lactone meglumine injection;Chinese Journal of Natural Medicines;2018-05

4. The pharmacokinetics study of ginkgolide A, B and the effect of food on bioavailability after oral administration of ginkgolide extracts in beagle dogs;Biomedical Chromatography;2018-03-08