Reactive oxygen species-scavenging hollow MnO2 nanozymes as carriers to deliver budesonide for synergistic inflammatory bowel disease therapy-Reference-Cited by-同舟云学术

Reactive oxygen species-scavenging hollow MnO2 nanozymes as carriers to deliver budesonide for synergistic inflammatory bowel disease therapy

Published:2022 Issue:2 Volume:10 Page:457-466
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Qiu Huiqiang¹,Gong Hengtai¹,Bao Yuheng¹,Jiang Hong²,Tong Weijun¹^ORCID

Affiliation:

1. MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China

2. Kidney Disease Center, College of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou 310027, China

Abstract

Hollow MnO2 nanozyme carriers loaded with budesonide can simultaneously scavenge excessive ROS and deliver anti-inflammatory drugs, resulting in synergistic IBD therapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D1BM01525G

Reference37 articles.

1. The global burden of IBD: from 2015 to 2025

3. World Gastroenterology Organization Practice Guidelines for the Diagnosis and Management of IBD in 2010

4. The glucocorticoid budesonide has protective and deleterious effects in experimental colitis in mice

5. Evaluation of separate role of intestine and liver in first pass metabolism of budesonide in rat

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