The influence of modified molecular (d/l-serine) chirality on the theragnostics of PAMAM-based nanomedicine for acute kidney injury-Reference-Cited by-同舟云学术

The influence of modified molecular (d/l-serine) chirality on the theragnostics of PAMAM-based nanomedicine for acute kidney injury

Published:2021 Issue:43 Volume:9 Page:9023-9030
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Kong Lulu¹,Fan Di¹,Zhou Lin¹^ORCID,Wei Shaohua¹²^ORCID

Affiliation:

1. College of Chemistry and Materials Science, Jiangsu Key Laboratory of Bio-functional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Nanjing Normal University, Nanjing, 210023, China

2. School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng, 224051, China

Abstract

Elevated H2O2 are early events in acute kidney injury (AKI). d- and l-serine modified poly(amidoamine) ( d-SP and l-SP) were synthesized. d-SP has superior AKI kidney accumulation ability to l-SP. d-SP was used as both a H2O2 probe and an anti-inflammatory drug carrier for AKI theragnostics.

Funder

Priority Academic Program Development of Jiangsu Higher Education Institutions

Jiangsu Collaborative Innovation Center for Climate Change

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01674A

Reference39 articles.

1. Towards Consensus in Timing of Kidney Replacement Therapy for Acute Kidney Injury?

2. Acute Kidney Injury in a Patient With Monoclonal Gammopathy