Design, synthesis and anticancer evaluation of imamine-1,3,5-triazine derivatives

Author:

Xue Xuan-Yi1,He Jing-Liang1,Li Rui1,Ding Bo2,Wu Wen-Long1,Cao Yao-Yao1,He Ran1,Hu Peng-Hong1,Ji Jing1,Shi Da-Hua1ORCID

Affiliation:

1. School of Pharmacy, Jiangsu Key Laboratory of Marine Bioresources and Environment, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang 222005, People's Republic of China

2. Jiangsu Henghai Pharmaceutical Research Institute Co., LTD, Lianyungang 222005, People's Republic of China

Abstract

Compound 4f not only showed strong inhibitory effects on migration, invasion, and adhesion, but also inhibited the in vivo proliferation of the MDA-MB-231 tumor xenografts.

Funder

Graduate Research and Innovation Projects of Jiangsu Province

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Reference46 articles.

1. Global cancer statistics

2. Middle East Panel for the Optimal Nutritional Management of Patients with Cancer , Clin. Nutr. ESPEN , 2023 , 55 , 267276

3. Recent applications of 2,4,6-trichloro-1,3,5-triazine and its derivatives in organic synthesis

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