Organocatalytic enantioselective Michael addition of cyclic hemiacetals to nitroolefins: a facile access to chiral substituted 5- and 6-membered cyclic ethers-Reference-Cited by-同舟云学术

Organocatalytic enantioselective Michael addition of cyclic hemiacetals to nitroolefins: a facile access to chiral substituted 5- and 6-membered cyclic ethers

Published:2015 Issue:16 Volume:13 Page:4769-4775
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhu Yadong¹²³⁴⁵,Qian Pengfei¹²³⁴⁵,Yang Jiyang¹²³⁴⁵,Chen Shaohua¹²³⁴⁵,Hu Yanwei¹²³⁴⁵,Wu Ping⁶⁷⁸⁵,Wang Wei⁹¹⁰¹¹¹²,Zhang Wei⁶⁷⁸⁵,Zhang Shilei¹²³⁴⁵

Affiliation:

1. Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases & Department of Medicinal Chemistry

2. College of Pharmaceutical Sciences

3. Soochow University

4. Suzhou 215123

5. China

6. School of Pharmacy

7. Fudan University

8. Shanghai 201203

9. Department of Chemistry and Chemical Biology

10. University of New Mexico

11. Albuquerque

12. USA

Abstract

An efficient aminocatalytic enantioselective Michael addition of readily available cyclic hemiacetals to nitroolefins has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00202H

Reference36 articles.

1. Advances in the Total Synthesis of Biologically Important Marine Macrolides

2. Tetrahydrofuran-Containing Macrolides: A Fascinating Gift from the Deep Sea

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