Carboxyboranylamino ethanol: unprecedented discovery of boron agents for neutron capture therapy in cancer treatment-Reference-Cited by-同舟云学术

Carboxyboranylamino ethanol: unprecedented discovery of boron agents for neutron capture therapy in cancer treatment

Published:2021 Issue:79 Volume:57 Page:10174-10177
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Zhu Yinghuai¹^ORCID,Cai Jianghong²,Hosmane Narayan S.³^ORCID,Suzuki Minoru⁴^ORCID,Uno Kazuko⁵,Zhang Yingjun¹,Takagaki Mao⁵⁶

Affiliation:

1. The State Key Laboratory of Anti-Infective Drug Development (No. 2015DQ780357), Sunshine Lake Pharma Co. Ltd, Dongguan 523871, China

2. School of Pharmacy and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China

3. Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, USA

4. Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka 590-0494, Japan

5. Louis Pasteur Centre for Medical Research, 103-5 Nakamonzen-machi, Sakyo-ku, Kyoto 606-8225, Japan

6. Graduate School of Human and Environmental Studies, Kyoto University, Kyoto 604-8232, Japan

Abstract

Carboxyboranylamino ethanol is cell membrane permeable and has low cytotoxicity. It shows high molecular docking scores and improved antitumor efficacy in vitro.

Funder

Kyoto University

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC03034E

Reference19 articles.

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3. Boron delivery agents for neutron capture therapy of cancer

4. Organic Nanotheranostics for Photoacoustic Imaging-Guided Phototherapy

5. Boron Chemistry for Medical Applications

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