Design and synthesis ofN1,N8-diacetylspermidine analogues having a linker with desired functional groups-Reference-Cited by-同舟云学术

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Design and synthesis ofN1,N8-diacetylspermidine analogues having a linker with desired functional groups

Published:2019 Issue:4 Volume:17 Page:867-875
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ohta Reiya¹²³⁴^ORCID,Oguro Akihiro⁵⁶⁷⁴,Nishimura Kazuhiro¹⁸⁹⁴,Murai Kenichi¹²³⁴^ORCID,Fujioka Hiromichi¹²³⁴^ORCID,Arisawa Mitsuhiro¹²³⁴^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Osaka University

3. Suita

4. Japan

5. Department of Molecular Biology

6. The Jikei University School of Medicine

7. Minato-ku

8. Chiba University

9. Chuo-ku

Abstract

The synthesis of newN¹,N⁸-diacetylspermidine (DiAcSpd) analogues having a linker with desired functional groups in the methylene skeleton, which have been designed by theoretical calculations, is described.

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Japan Science and Technology Corporation

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB02900H

Reference28 articles.

1. R. Alcazar and A.Tiburcio , Polyamines -Methods and Protocols- , Humana Press , 2018

2. T. Kusano and H.Suzuki , Polyamines -A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism- , Springer , Japan , 2015

3. Spermidine in health and disease

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