Design criteria for minimalist mimics of protein–protein interface segments-Reference-Cited by-同舟云学术

Design criteria for minimalist mimics of protein–protein interface segments

Published:2019 Issue:4 Volume:17 Page:908-915
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Taechalertpaisarn Jaru¹²³⁴^ORCID,Lyu Rui-Liang¹²³⁴^ORCID,Arancillo Maritess¹²³⁴^ORCID,Lin Chen-Ming¹²³⁴^ORCID,Jiang Zhengyang¹²³⁴^ORCID,Perez Lisa M.⁵²³⁴,Ioerger Thomas R.⁶²³⁴,Burgess Kevin¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Laboratory For Molecular Simulation

2. Texas A & M University

3. College Station

4. USA

5. Laboratory For Molecular Simulation

6. Department of Computer Science

Abstract

We present several critical design criteria of minimalist peptidomimetics deduced via extensive computational and data-mining studies on nine representative mimic designs.

Funder

National Science Foundation

National Institutes of Health

Welch Foundation

U.S. Army

Cancer Prevention and Research Institute of Texas

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB02901F

Reference27 articles.

1. Modulators of Protein–Protein Interactions

2. In silico design of low molecular weight protein–protein interaction inhibitors: Overall concept and recent advances

3. Protein–Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

4. H. Yin and A. D.Hamilton , Protein Secondary Structure Mimetics as Modulators of Protein-Protein and Protein-Ligand Interactions, in Chemical Biology , Wiley-VCH-VCH Verlag , 2008

5. Minimalist and universal peptidomimetics

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