Genomics-driven discovery of chiral triscatechol siderophores with enantiomeric Fe(iii) coordination-Reference-Cited by-同舟云学术

Genomics-driven discovery of chiral triscatechol siderophores with enantiomeric Fe(iii) coordination

Published:2021 Issue:37 Volume:12 Page:12485-12493
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Stow Parker R.¹^ORCID,Reitz Zachary L.¹^ORCID,Johnstone Timothy C.²^ORCID,Butler Alison¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California Santa Barbara, CA 93106-9510, USA

2. Department of Chemistry and Biochemistry, University of California Santa Cruz, CA 95064, USA

Abstract

Synthesis and genome mining leverage access to diastereomers of the siderophore cyclic trichrysobactin. Computational modeling and CD spectroscopy address effects that ligand-based stereochemistry exerts on the configuration at Fe(iii).

Funder

National Science Foundation

Hellman Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC03541J

Reference38 articles.

1. Enzymatic Hydrolysis of Trilactone Siderophores: Where Chiral Recognition Occurs in Enterobactin and Bacillibactin Iron Transport

2. Stereospecificity of the ferric enterobactin receptor of Escherichia coli K-12.

3. Corynebactin and Enterobactin: Related Siderophores of Opposite Chirality

4. Determination of the Molecular Structures of Ferric Enterobactin and Ferric Enantioenterobactin Using Racemic Crystallography

5. Chrysobactin Siderophores Produced by Dickeya chrysanthemi EC16

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