Combining the platinum(ii) drug candidate kiteplatin with 1,10-phenanthroline analogues

Author:

Pages Benjamin J.1234ORCID,Sakoff Jennette564ORCID,Gilbert Jayne564ORCID,Zhang Yingjie784ORCID,Kelly Sharon M.910111213ORCID,Hoeschele James D.14151617,Aldrich-Wright Janice R.1234ORCID

Affiliation:

1. Nanoscale Organisation and Dynamics Group

2. Western Sydney University

3. Campbelltown

4. Australia

5. Calvary Mater Newcastle

6. Waratah

7. Australian Nuclear Science and Technology Organisation

8. Kirrawee DC

9. Institute of Molecular

10. Cell and Systems Biology

11. College of Medical

12. Veterinary and Life Sciences

13. University of Glasgow

14. Department of Chemistry

15. Eastern Michigan University

16. Ypsilanti

17. USA

Abstract

Drug candidate kiteplatin has been combined with analogues of 1,10-phenanthroline, and the DNA affinity and cytotoxicity have been assessed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference36 articles.

1. Australian Institute of Health and Welfare and Australasian Association of Cancer Registries , Cancer in Australia 2017 , Australian Institute of Health and Welfare , Canberra , 2017

2. Cancer statistics, 2017

3. The status of platinum anticancer drugs in the clinic and in clinical trials

4. The state-of-play and future of platinum drugs

5. B. H. Harper , F.Li , R.Beard , K. B.Garbutcheon-Singh , N. S.Ng and J. R.Aldrich-Wright , in Supramolecular Systems in Biomedical Fields , ed. H. J. Schneider , Royal Society of Chemistry , Cambridge, UK , 1st edn, 2013 , ch. 9

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