Manipulating macrophage polarization with nanoparticles to control metastatic behavior in heterotypic breast cancer micro-tissues <i>via</i> exosome signaling-Reference-Cited by-同舟云学术

Manipulating macrophage polarization with nanoparticles to control metastatic behavior in heterotypic breast cancer micro-tissues via exosome signaling

Published:2024 Issue:1 Volume:16 Page:394-410
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Sungu Mustafa¹,Isik Melis¹^ORCID,Güler Ülkü²,Eylem Cemil Can³,Eskizengin Hakan⁴,Nemutlu Emirhan³^ORCID,Salih Bekir²,Derkus Burak¹⁵^ORCID

Affiliation:

1. Stem Cell Research Lab, Department of Chemistry, Faculty of Science, Ankara University, 06560 Ankara, Turkey

2. Department of Chemistry, Faculty of Science, Hacettepe University, 06800 Ankara, Turkey

3. Analytical Chemistry Division, Faculty of Pharmacy, Hacettepe University, Ankara 06230, Turkey

4. Department of Biology, Faculty of Science, Ankara University, 06560 Ankara, Turkey

5. Neuroscience and Neurotechnology Excellence Joint Application and Research Center (NEUROM), 06560 Ankara, Turkey

Abstract

Palladium nanoparticles-induced M1-like macrophages release exosomes (PdNPs-Exo) with anti-tumorigenic bioactivity. PdNPs-Exo downregulates metastatic genes and increases drug sensitivity in heterotypic breast cancer models.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR04980A

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