Amikacin@SiO<sub>2</sub> core@shell nanocarriers to treat pulmonal bacterial infections-Reference-Cited by-同舟云学术

Amikacin@SiO₂ core@shell nanocarriers to treat pulmonal bacterial infections

Published:2023 Issue:24 Volume:11 Page:5460-5468
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Rutschmann Mark¹,Redinger Natalja²³^ORCID,Schaible Ulrich E.²³⁴^ORCID,Feldmann Claus¹^ORCID

Affiliation:

1. Institute of Inorganic Chemistry, Karlsruhe Institute of Technology (KIT), Engesserstraße 15, 76131 Karlsruhe, Germany

2. Research Center Borstel, Leibniz Lung Center, Priority Area Infections, Division Cellular Microbiology, Parkallee 1-40, 23845 Borstel, Germany

3. German Center for Infection Research (DZIF), Site Hamburg-Lübeck-Borstel-Riems, 23845 Borstel, Germany

4. University of Luebeck, 23562 Luebeck, Germany

Abstract

AMC@SiO2 core@shell nanocarriers (AMC: amikacin) with 200 nm AMC core, 20 nm silica shell, and unprecedented AMC load (80%) show high activity against Mycobacterium tuberculosis and Mycobacterium abscessus as pulmonal, often multiresistant bacteria.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB02609K

Reference41 articles.

1. Breaking the barriers for the delivery of amikacin: Challenges, strategies, and opportunities

2. Amikacin: Uses, Resistance, and Prospects for Inhibition

3. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

4. Inhaled Liposomal Antimicrobial Delivery in Lung Infections

5. The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors

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