Indoline hemiaminals: a platform for accessing anthranilic acid derivatives through oxidative deformylation

Author:

Tokushige Keisuke1,Kobori Yuito1,Asai Shota2ORCID,Abe Takumi1ORCID

Affiliation:

1. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima-naka, Kita-ku, Okayama 7008530, Japan

2. School of Pharmacy, Shujitsu University, 1-6-1, Nishigawara, Naka-ku, Okayama, 7038516, Japan

Abstract

Herein, we introduce a new synthetic protocol using 2-aminobenzoyl surrogates, allowing concise entry to decorated 2-aminobenzoyl derivatives in the absence of transition metals, acid chlorides, and specific reagents.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Corporation

Publisher

Royal Society of Chemistry (RSC)

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