Synthetic lipo-polylysine with anti-cancer activity-Reference-Cited by-同舟云学术

Synthetic lipo-polylysine with anti-cancer activity

Published:2023 Issue:19 Volume:11 Page:6611-6618
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Yi Xuan¹²,Wan Pengqi¹²,Shen Wei³,Zhang Xiaonong¹²,Zhang Peng¹²,Xiao Chunsheng¹²^ORCID

Affiliation:

1. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China

2. Jilin Biomedical Polymers Engineering Laboratory, Changchun 130022, P. R. China

3. School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, P. R. China

Abstract

A cationic lipo-polylysine C12-PLL13 can interact with negatively charged tumor cell membrane and induce cell necrosis by triggering membrane perforation and disintegration, offering a distinct therapeutic mechanism from traditional antitumor drugs.

Funder

National Natural Science Foundation of China

Jilin Scientific and Technological Development Program

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM01099F

Reference33 articles.

1. Chemotherapy and the war on cancer

2. Biological Stimuli-responsive Polymer Systems: Design, Construction and Controlled Self-assembly

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