Regio- and diastereoselective synthesis of spiropyrroloquinoxaline grafted indole heterocyclic hybrids and evaluation of their anti-Mycobacterium tuberculosis activity-Reference-Cited by-同舟云学术

Regio- and diastereoselective synthesis of spiropyrroloquinoxaline grafted indole heterocyclic hybrids and evaluation of their anti-Mycobacterium tuberculosis activity

Published:2020 Issue:40 Volume:10 Page:23522-23531
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Arumugam Natarajan¹²³⁴⁵^ORCID,Almansour Abdulrahman I.¹²³⁴⁵,Kumar Raju Suresh¹²³⁴⁵^ORCID,Mohammad Ali Al-Aizari Abdul Jaleel¹²³⁴⁵,Alaqeel Shatha Ibrahim¹²⁶⁷⁵,Kansız Sevgi⁸⁹¹⁰¹¹¹²^ORCID,Krishna Vagolu Siva¹³¹⁴¹⁵¹⁶¹⁷,Sriram Dharmarajan¹³¹⁴¹⁵¹⁶¹⁷,Dege Necmi¹⁸¹⁹²⁰¹¹¹²^ORCID

Affiliation:

1. Department of Chemistry

2. College of Science

3. King Saud University

4. Riyadh 11451

5. Saudi Arabia

6. King Saud University (034)

7. Riyadh 11495

8. Department of Fundamental Sciences

9. Faculty of Engineering

10. Samsun University

11. Samsun

12. Turkey

13. Medicinal Chemistry and Antimycobacterial Research Laboratory

14. Pharmacy Group

15. Birla Institute of Technology & Science-Pilani

16. Hyderabad Campus

17. Hyderabad 500078

18. Department of Physics

19. Faculty of Arts and Sciences

20. Ondokuz Mayıs University

Abstract

An efficient and eco compatible approach for the regio- and stereoselective synthesis of structurally diverse novel spiropyrrolidine tethered indole hybrids in excellent yields employing a one-pot multicomponent 1,3-dipolar cycloaddition strategy.

Funder

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA02525A

Reference42 articles.

1. Tuberculosis: A disease without boundaries

2. World Health Organization , Global Tuberculosis Report , 2019 , http://www.who.int/tb/publications/global_report/en/

3. Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity

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