The short route to chalcogenurea-substituted 3<i>a</i>,6-epoxyisoindoles <i>via</i> an intramolecular Diels–Alder furan (IMDAF) reaction. Antibacterial and antifungal activity-Reference-Cited by-同舟云学术

The short route to chalcogenurea-substituted 3a,6-epoxyisoindoles via an intramolecular Diels–Alder furan (IMDAF) reaction. Antibacterial and antifungal activity

Published:2024 Issue:29 Volume:48 Page:12947-12959
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Mertsalov Dmitriy F.¹,Shchevnikov Dmitriy M.¹,Lovtsevich Lala V.¹,Novikov Roman A.²^ORCID,Khrustalev Victor N.¹³^ORCID,Grigoriev Mikhail S.⁴,Romanycheva Anna A.⁵,Shetnev Anton A.⁶,Bychkova Olga P.⁷,Trenin Alexey S.⁷,Zaytsev Vladimir P.¹^ORCID

Affiliation:

1. RUDN University, 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation

2. V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow, 119991, Russian Federation

3. Zelinsky Institute of Organic Chemistry of RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation

4. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky pr. 31, bld. 4, 119071, Moscow, Russian Federation

5. Pharmaceutical Technology Transfer Center, Yaroslavl State Pedagogical University Named After K. D. Ushinsky, 108/1 Republican St., 150000, Yaroslavl, Russian Federation

6. Moscow Institute of Physics and Technology 1 “A” Kerchenskaya St., Moscow, 117303, Russian Federation

7. Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russian Federation

Abstract

A concise preparative IMDAF strategy for the synthesis of chalcogenurea-substituted 3a,6-epoxyisoindoles, which display antifungal and antibacterial activity, starting from readily available materials was proposed.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D4NJ01174K

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