An intelligent peptide recognizes and traps <i>Mycobacterium tuberculosis</i> to inhibit macrophage phagocytosis-Reference-Cited by-同舟云学术

An intelligent peptide recognizes and traps Mycobacterium tuberculosis to inhibit macrophage phagocytosis

Published:2023 Issue:1 Volume:11 Page:180-187
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wang Gui-Yuan¹²,Lu Bin³,Cui Xu³,Li Guang³,Zhang Kuo²^ORCID,Zhang Qing-Shi²,Cui Xin¹²,Qi Gao-Feng¹²,Liang Qi-Lin²,Luo Xiao-Bo³,Xu Huan-Ge²,Xiao Li⁴,Wang Lei²^ORCID,Li Litao³

Affiliation:

1. Department of Graduate, Hebei North University, Zhangjiakou, 075000, Hebei Province, China

2. CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing, 100190, China

3. Department of Orthopedics, The 4th Medical Center of Chinese PLA General Hospital, No. 51 Fucheng road, Beijing, 100091, China

4. Institute of Respiratory and Critical Medicine, the Eighth Medical Center of PLA General Hospital, Beijing 100091, China

Abstract

We report an intelligent anti-microbial peptide (bis-pyrene-KLVFF-WHSGTPH) that can recognize and trap Mycobacterium tuberculosis, inhibiting the macrophage phagocytosis process.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB01764D

Reference52 articles.

1. Global reporting on tuberculosis preventive treatment among contacts

2. The WHO Global Tuberculosis 2021 Report – not so good news and turning the tide back to End TB

3. Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis

4. Macrophages in tuberculosis: friend or foe

5. Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro

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