Nitric oxide releasing coatings for the prevention of viral and bacterial infections

Author:

Aveyard Jenny1,Richards Siobhan2,Li Man1,Pitt Graeme1ORCID,Hughes Grant L.2ORCID,Akpan Asangaedem34,Akhtar Riaz1,Kazaili Ahmed5,D'Sa Raechelle A.1ORCID

Affiliation:

1. School of Engineering, University of Liverpool, Harrison Hughes Building, Brownlow Hill, Liverpool, L69 3GH, UK

2. Departments of Vector Biology and Tropical Disease Biology, Centre for Neglected Tropical Disease, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK

3. Department of Musculoskeletal & Ageing Sciences, University of Liverpool, Liverpool L69 3GL, UK

4. Liverpool University Hospitals NHS FT, Liverpool L7 8XP, UK

5. Department of Biochemistry & Systems Biology, University of Liverpool, Liverpool, L69 7ZB, UK

Abstract

Healthcare associated infections are a significant burden worldwide contributing to morbidity and mortality. We report on the development of nitric oxide releasing polymer coatings that have demonstrated excellent antibacterial/antiviral efficacy.

Funder

Biotechnology and Biological Sciences Research Council

Royal Society

National Institute for Health Research

Bill and Melinda Gates Foundation

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

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