A combined solid- and solution-phase approach provides convenient access to analogues of the calcium-dependent lipopeptide antibiotics-Reference-Cited by-同舟云学术

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A combined solid- and solution-phase approach provides convenient access to analogues of the calcium-dependent lipopeptide antibiotics

Published:2014 Issue:6 Volume:12 Page:913-918
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hart Peter 't¹²³⁴,Kleijn Laurens H. J.¹²³⁴,de Bruin Gerjan⁵⁶⁷,Oppedijk Sabine F.¹²³⁴,Kemmink Johan¹²³⁴,Martin Nathaniel I.¹²³⁴

Affiliation:

1. Medicinal Chemistry & Chemical Biology Group

2. Utrecht Institute for Pharmaceutical Sciences

3. Utrecht University

4. 3584 CG Utrecht, The Netherlands

5. Bio-organic Synthesis Group

6. Leiden Institute of Chemistry

7. 2333 CC Leiden, The Netherlands

Abstract

A synthetic route combining solid- and solution-phase techniques allows for the rapid preparation of daptomycin analogues.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C3OB42238K

Reference24 articles.

1. Systems-level antimicrobial drug and drug synergy discovery

2. The antibiotic resistome: the nexus of chemical and genetic diversity

3. Mechanisms of in-vitro-selected daptomycin-non-susceptibility in Staphylococcus aureus

4. Antimicrobial susceptibility of Gram-positive bacteria isolated from US medical centers: results of the Daptomycin Surveillance Program (2007–2008)

5. Antimicrobial activity of daptomycin and selected comparators tested against bloodstream Staphylococcus aureus isolates from hemodialysis patients

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