NHC-catalyzed enantioselective synthesis of dihydropyran-4-carbonitriles bearing all-carbon quaternary centers

Author:

Wu Qiuju12345,Li Chengcheng12345,Wang Weihong12345,Wang Hongling12345,Pan Dingwu12345,Zheng Pengcheng12345ORCID

Affiliation:

1. Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering

2. Key Laboratory of Green Pesticide and Agricultural Bioengineering Ministry of Education

3. Guizhou University

4. Guiyang 550025

5. China

Abstract

A LiCl assisted, carbene-catalyzed oxidative reaction for the synthesis of dihydropyran-4-carbonitriles bearing all-carbon quaternary centers was developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference74 articles.

1. R. C. Larock , Comprehensive Organic Transformations: A Guide to Functional Group Preparations, VCH, New York, 1989

2. J. F. Hartwig , Organotransition Metal Chemistry: From Bonding to Catalysis, Univ Science Books, 2010, 102

3. C. E. Mabermann , in: Encyclopedia of Chemical Technology, ed. J. I. Kroschwitz, Wiley, New York, 1991, 251

4. Additions to Metal-Activated Organonitriles

5. P. Pollak , G.Romeder, F.Hagedorn and H.-P.Gelbke, Nitriles, in: Ullman's Encycloped-Ia of Industrial Chemistry, Wiley-VCH, Weinheim, 2012

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