Nickel(ii)-promoted specific hydrolysis of zinc finger proteins-Reference-Cited by-同舟云学术

Nickel(ii)-promoted specific hydrolysis of zinc finger proteins

Published:2018 Issue:8 Volume:10 Page:1089-1098
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Belczyk-Ciesielska Agnieszka¹²³⁴,Csipak Brigitta⁵⁶⁷⁸,Hajdu Bálint⁵⁶⁷⁸,Sparavier Aleksandra¹²³⁴,Asaka Masamitsu N.⁹¹⁰¹¹¹²¹³,Nagata Kyosuke⁹¹⁰¹¹¹²¹³,Gyurcsik Béla⁵⁶⁷⁸^ORCID,Bal Wojciech¹²³⁴^ORCID

Affiliation:

1. Institute of Biochemistry and Biophysics

2. Polish Academy of Sciences

3. Warsaw

4. Poland

5. Department of Inorganic and Analytical Chemistry

6. University of Szeged

7. Szeged H-6720

8. Hungary

9. Nagata Special Laboratory

10. Faculty of Medicine

11. University of Tsukuba

12. Tsukuba 305-8575

13. Japan

Abstract

The (S/T)XH sequence in Cys₂His₂zinc fingers can be hydrolytically cleaved by Ni(ii) ions. This reaction can be applied for purification, inhibition or activation of designed zinc finger fusion proteins.

Funder

Fundacja na rzecz Nauki Polskiej

Magyar Tudományos Akadémia

Polska Akademia Nauk

Nemzeti Kutatási, Fejlesztési és Innovációs Hivatal

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MT/C8MT00098K

Reference78 articles.