Engineering of a functional pancreatic acinus with reprogrammed cancer cells by induced PTF1a expression-Reference-Cited by-同舟云学术

Engineering of a functional pancreatic acinus with reprogrammed cancer cells by induced PTF1a expression

Published:2021 Issue:19 Volume:21 Page:3675-3685
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Venis Stephanie M.¹,Moon Hye-ran¹,Yang Yi²,Utturkar Sagar M.³^ORCID,Konieczny Stephen F.²³^ORCID,Han Bumsoo¹³⁴^ORCID

Affiliation:

1. School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA

2. Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA

3. Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA

4. Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA

Abstract

We present a microfluidic model of the normal pancreatic acinus with epithelial duct and acinar cavity structure using reprogrammed pancreatic cancer cells by inducing PTF1a gene.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D1LC00350J

Reference51 articles.

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