Alginate nanoparticle synthesis using n-heptane and isopropyl myristate/AOT reverse micelles: the impact of the non-polar solvent, water content, and pH on the particle size and cross-linking efficiency

Abstract

The synthesis of monodisperse and stable alginate nanoparticles (ALG-NPs) was achieved through the crosslinking of sodium alginate with Ca2+ ions within sodium bis(2-ethylhexyl)sulfosuccinate (AOT) reverse micelles (RMs) as nano-templates.