Targeted and efficient delivery of rifampicin to macrophages involved in non-tuberculous mycobacterial infection <i>via</i> mannosylated solid lipid nanoparticles-Reference-Cited by-同舟云学术

Targeted and efficient delivery of rifampicin to macrophages involved in non-tuberculous mycobacterial infection via mannosylated solid lipid nanoparticles

Published:2023 Issue:17 Volume:5 Page:4536-4545
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Chae Jayoung¹²,Kang Seung Hyun³,Kim Jiwon¹,Choi Yonghyun¹²³,Kang Shin Hyuk³,Choi Jonghoon¹²^ORCID

Affiliation:

1. School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea

2. Feynman Institute of Technology, Nanomedicine Corporation, Seoul 06974, Republic of Korea

3. Departments of Plastic and Reconstructive Surgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06973, Republic of Korea

Abstract

Targeting mannose receptors expressed on the M. intracellulare infected macrophages with rifampin-loaded mannosylated solid lipid nanoparticles (Man-RIF SLNs) can significantly increase drug delivery efficiency with minimal side effects.

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Ministry of Environment

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NA/D3NA00320E

Reference32 articles.

1. Inhaled Antibiotics for Mycobacterial Lung Disease

2. Role of ethambutol and rifampicin in the treatment of Mycobacterium avium complex pulmonary disease

3. Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation

4. Mechanisms of Antibiotic Tolerance in Mycobacterium avium Complex: Lessons From Related Mycobacteria

5. High mortality in patients with Mycobacterium avium complex lung disease: a systematic review

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