The neuroprotective effects of isoquercitrin purified from apple pomace by high-speed countercurrent chromatography in the MPTP acute mouse model of Parkinson's disease

Author:

Liu Cong1234,Wang Wenjuan1234,Li Hao5674,Liu Jiangang5674,Zhang Peng5674,Cheng Yong89101112ORCID,Qin Xiaoyan89101112,Hu Yang89101112ORCID,Wei Yun1234ORCID

Affiliation:

1. State Key Laboratory of Chemical Resource Engineering

2. Beijing University of Chemical Technology

3. Beijing

4. China

5. Xiyuan Hospital

6. China Academy of Chinese Medical Sciences

7. Beijing 100091

8. Key Laboratory of Ethnomedicine for Ministry of Education

9. Center on Translational Neuroscience

10. College of Life and Environmental Sciences

11. Minzu University of China

12. Beijing 100081

Abstract

Isoquercitrin was isolated from apple pomace by HSCCC and proved to have neuroprotective effects on Parkinson's mice induced by MPTP.

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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