Cav2.2 and Cav3.1 calcium channel inhibitors from Valeriana jatamansi Jones-Reference-Cited by-同舟云学术

Cav2.2 and Cav3.1 calcium channel inhibitors from Valeriana jatamansi Jones

Published:2017 Issue:72 Volume:7 Page:45878-45884
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Jiang He-Hai¹²³⁴⁵,Dong Fa-Wu⁶⁷⁴⁸⁹,Zhou Jun⁶⁷⁴⁸⁹,Hu Jiang-Miao⁶⁷⁴⁸⁹,Yang Jian¹²³⁴⁵,Nian Yin¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences

2. Ion Channel Research and Drug Development Center

3. Kunming Institute of Zoology

4. Chinese Academy of Sciences

5. Kunming 650223

6. State Key Laboratory of Phytochemistry and Plant Resources in West China

7. Kunming Institute of Botany

8. Kunming 650201

9. P. R. China

Abstract

In China, the roots and rhizomes of Valeriana jatamansi Jones are traditionally used to treat gastrointestinal and rheumatic pain. In the present study, a number of N- and T-type calcium channel inhibitors were initially isolated and identified.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA07327E

Reference23 articles.

1. Ziconotide, an Intrathecally Administered N-Type Calcium Channel Antagonist for the Treatment of Chronic Pain

2. Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain

3. TTA-P2 Is a Potent and Selective Blocker of T-Type Calcium Channels in Rat Sensory Neurons and a Novel Antinociceptive Agent

4. Targeting voltage-gated calcium channels in neurological and psychiatric diseases

5. Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment

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