Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes-Reference-Cited by-同舟云学术

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Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes

Published:2016 Issue:9 Volume:40 Page:7421-7430
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Stauffert Fabien¹²³⁴⁵,Bodlenner Anne¹²³⁴⁵,Nguyet Trinh Thi Minh⁶⁷³⁸⁵,García-Moreno M. Isabel⁹¹⁰¹¹¹²¹³,Ortiz Mellet Carmen⁹¹⁰¹¹¹²¹³^ORCID,Nierengarten Jean-François⁶⁷³⁸⁵,Compain Philippe¹²³⁴⁵

Affiliation:

1. Laboratoire de Synthèse Organique et Molécules Bioactives (SYBIO)

2. Université de Strasbourg/CNRS (UMR 7509)

3. Ecole Européenne de Chimie

4. Polymères et Matériaux (ECPM)

5. 67087 Strasbourg Cedex 2

6. Laboratoire de Chimie des Matériaux Moléculaires

7. Université de Strasbourg et CNRS (UMR 7509)

8. Polymères et Matériaux

9. Departamento de Química Orgánica

10. Facultad de Química

11. Universidad de Sevilla

12. Profesor García González 1

13. Sevilla

Abstract

Multivalent C-glycosides based on C₆₀ or β-cyclodextrin cores were designed to probe the influence of inhitopes in glycosidase binding events.

Funder

Institut Universitaire de France

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NJ/C6NJ01311B

Reference64 articles.

1. Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

2. The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters

3. Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

4. The Multivalent Effect in Glycosidase Inhibition: A New, Rapidly Emerging Topic in Glycoscience

5. Multivalent Inhibitors for Carbohydrate-Processing Enzymes: Beyond the “Lock-and-Key” Concept

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