Permeation of nanoparticles across the intestinal lipid membrane: dependence on shape and surface chemistry studied through molecular simulations
Author:
Affiliation:
1. Physical Science Research Area
2. Tata Research Development and Design Centre
3. TCS Research
4. Tata Consultancy Services
5. Pune 411013
6. School of Engineering and Applied Sciences
7. Wyss Institute Harvard University
8. USA
Abstract
In-silico design & testing of nanoparticles for oral drug delivery applications.
Funder
Tata Consultancy Services
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2020/NR/C9NR09947F
Reference77 articles.
1. Measurement of gastrointestinal pH profiles in normal ambulant human subjects.
2. Surface Structure of Intestinal Epithelium
3. Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight
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